Optical techniques for cervical neoplasia detection

• Tatiana Novikova

Beilstein J. Nanotechnol. 2017, 8, 1844–1862, doi:10.3762/bjnano.8.186

• images from over 60 patients obtained by fluorescence confocal endomicroscopy was used for ex vivo and in vivo studies of four types of cervical tissue relevant for the diagnostics: normal columnar epithelium, normal and precancerous squamous epithelium, and stromal tissue [80]. Researchers acknowledged

• , photoacoustic imaging), probe different tissue properties that may serve as optical biomarkers for diagnosis. Both the advantages and drawbacks of these techniques for the diagnosis of cervical precancerous lesions are discussed and compared. Keywords: cervical intraepithelial neoplasia; confocal

• endomicroscopy; Mueller polarimetry; nanotheranostics; optical coherence tomography; optical spectroscopy; Raman spectroscopy; Review Introduction Cervical cancer remains one of the major health issues, causing 266000 deaths of women worldwide in 2012 [1]. While the highest incidence rate of cervical cancers